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What we do
Pioneering the future of cardiac care.​
We develop cutting-edge predictive modeling simulations that provide interventional cardiologists with precise insights into patient-specific heart conditions, reducing risks and enhancing outcomes. Our innovative technology empowers medical professionals to make informed decisions, ensuring safer and more successful heart surgeries. We’re committed to advancing the art of cardiac care, one simulation at a time.​
Groundbreaking Technology
Our digital twin simulations offer innovative techniques for assessing otherwise undetectable heart procedure complications.
Personalized Simulations
Our one-of-a-kind predictive modeling simulations are completely customizable to the patient.
Benefits for Patients & Physicians
Our solutions offer increased patient safety and physician satisfaction.
DASI Simulations is pleased to provide simulations for health systems in these states, and we continue to extend our reach to hospitals worldwide:
Announcing the DASI app - the newest addition to our technology
Unlock a new era in structural heart disease planning with the DASI Simulations Treatment App—an innovative addition to the DASI technology family. This app is a game-changer, offering clinicians unparalleled capabilities to visualize and optimize treatment options, ultimately leading to better patient outcomes.
Watch our predictive modeling simulation technology IN ACTION
- THE LATEST IN SCIENTIFIC ACHIEVEMENTS
These publications highlight the latest scientific achievements of our proprietary technology, which empowers surgeons with precise insights into patient-specific heart conditions before surgery. As we continue to push the boundaries of medical science, DASI Simulations remains at the forefront of revolutionizing cardiac care, ultimately leading to safer and more successful outcomes for patients worldwide.
Deformation of Transcatheter Aortic Valve Prostheses: Implications for Hypoattenuating Leaflet Thickening and Clinical Outcomes | 2022
Nonuniform expansion of TAVR prostheses resulting in frame deformation, asymmetric leaflet, and smaller neosinus volume is related to occurrence of HALT in patients who undergo TAVR. These data may have implications for both prosthesis valve design and deployment techniques to improve clinical outcomes for these patients.
Incomplete Expansion of Transcatheter Aortic Valves is Associated with Propensity for valve thrombosis | 2020
Incomplete expansion of TAVs increases blood stasis on the surface of TAV leaflets. Regions of blood stasis promote platelet activation and thrombotic events. TAV underexpansion can therefore increase the risk of leaflet thrombosis in patients with transcatheter aortic valve replacement.
Inter- and Intra-Observer Repeatability of Aortic Annulus Measurements on Screening CT for TAVR: Implications for Appropriate Device Sizing | 2018
Aortic annulus CT measurements for TAVR are highly reproducible. Multi-reader strategies provide higher precision than evaluations from single readers with different levels of experience and could effectively be implemented with two readers and an optional third reader in a clinical setting.
Reproducibility of Aortic Annulus Measurements by Computed Tomography | 2014
A systematic approach to generate a double oblique imaging plane exactly aligned with the aortic annulus demonstrates high interobserver and intraobserver agreements for derived measurements which are not influenced by aortic root calcification.
An In Vitro Evaluation of the Impact of Eccentric Deployment on Transcatheter Aortic Valve Hemodynamics | 2014
Patients with aortic stenosis present with calcium deposits on the native aortic valve, which can result in non-concentric expansion of Transcatheter Aortic Valve Replacement (TAVR) stents. The objective of this study is to evaluate whether eccentric deployment of TAVRs lead to turbulent blood flow and blood cell damage. Particle Image Velocimetry was used to quantitatively characterize fluid velocity fields, shear stress and turbulent kinetic energy downstream of TAVRs deployed in circular and eccentric orifices representative of deployed TAVRs in vivo. Effective orifice area (EOA) and mean transvalvular pressure gradient (TVG) values did not differ substantially in circular and eccentric deployed valves, with only a minor decrease in EOA observed in the eccentric valve (2.0 cm2 for circular, 1.9 cm2 for eccentric). Eccentric deployed TAVR lead to asymmetric systolic jet formation, with increased shear stresses (circular = 97 N/m2 vs. eccentric = 119 N/m2) and regions of turbulence intensity (circular = 180 N/m2 vs. eccentric = 230 N/m2) downstream that was not present in the circular deployed TAVR. The results of this study indicate that eccentric deployment of TAVRs can lead to altered flow characteristics and may potentially increase the hemolytic potential of the valve, which were not captured through hemodynamic evaluation alone.
Cardiologists Trust in DASI
Real Voices, Real Results: Heart Surgeons Applaud DASI Simulations
*This video reflects the opinions of Dr. Thourani and not that of Piedmont Healthcare.
HEAR WHAT
THEY ARE SAYING
"This 3D reconstruction modeling has directly informed the way we approach heart valve replacement procedures."
Interventional CardiologistWexner Medical Center
The Ohio State University
TRUSTED BY MANY HEALTHCARE INSTITUTIONS
